|Classification and external resources|
File:Diseases of Swine 25-5.png|
Foot-and-mouth disease. Acantholysis in a sample of a skin vesicle. Necrosis of the stratum spinosum can be observed, and keratinocytes floating in the vesicular fluid (spongiosa).
|ICD-10||L11.9 (ILDS L11.900)|
Acantholysis is the loss of intercellular connections resulting in loss of cohesion between keratinocytes, seen in diseases such as pemphigus vulgaris. It is absent in bullous pemphigoid, making it useful for differential diagnosis.
This histological feature is also seen in herpes simplex infections (HSV 1 and 2).
- Skin lesion
- Skin disease
- List of cutaneous conditions