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Epizootic lymphangitis

Epizootic lymphangitis is a contagious lymphangitis disease of horses and mules caused by caused by the fungus Histoplasma farciminosum.[1] Cattle are also susceptible, but more resistant to the disease than equids.

See also Glanders and Equine Lymphangitis.



In the it is a notifiable disease; the OIE classify it as a List B Disease. These are diseases on "the List of transmissible diseases which are considered to be of socio-economic and/or public health importance within countries and which are significant in the international trade of animals and animal products". Reports of these diseases are normally submitted once a year.[2]


Epizootic Lymphangitis usually presents with the following symptoms:

  • Skin eruption, usually on legs, occasionally head or neck, rarely other body parts.
  • The lymph vessels in the skin stand out prominently, and small hard nodules approximately 1cm (1/2") in diameter appear on their course.
  • The nodules suppurate forming abscesses and discharge a thick yellow pus. Proud flesh grows from the wounds, the lymph vessels around being inflamed, and the eruption gradually extends.
  • The neighbouring glands are swollen and hard. The ulcers heal with difficulty, even under treatment, and they may break out again after an apparent cure had been effected.[3]


This disease is distinguished from glanders/farcy by the presence of the Histoplasma organisms in the pus, and failure of the mallein test to produce a reaction. Both Glanders and epizootic lymphangitis may be present in the same animal. Serology can be used to assist diagnosis.


Control of the disease is usually through elimination of the infection. This is achieved by culling infected horses and application of strict hygiene practices to prevent spread of the organism.

Vaccination has been utilised on a limited scale in areas where enzootic lymphangitis is endemic, e.g. Iraq, but is not authorised for widespread use.[4]


  1. OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2004 Chapter 2.5.13, [1]
  2. OIE Terrestrial Animal Health Code 2003 [2]
  3. DEFRA (UK) [3]
  4. OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals (2004), Chapter 2.5.13 [4]


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