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Iris cyst

An iris cyst, or uveal cyst, is a small hollow structure either attached to the iris of the eye or floating free in the anterior chamber. An iris cyst is composed of a single cell layer of epithelium and is filled with fluid.[1] It is most commonly seen as secondary to inflammation in the eye, especially with canine glaucoma. They are most commonly seen in dogs. Golden Retrievers, Labrador Retrievers, and Boston Terriers are the most commonly affected breeds.[2] Iris cysts also occur in cats and horses. The cysts are usually free floating in dogs, attached to the pupillary margin in cats, and present in the interior of the iris (especially blue irides) in horses.[3]

Iris cysts usually cause no symptoms, but in large numbers they can cause glaucoma by obstructing the drainage angle of the eye. Golden Retrievers may have a higher rate of glaucoma associated with iris cysts.[4]

Iris cysts need to be differentiated from iris melanoma, a tumor, by demonstrating their hollowness. A light directed at an iris cyst will cause it to transilluminate. Iris cysts can be collapsed if necessary by a veterinarian with a small needle carefully introduced into the anterior chamber.[5] The cysts may also be destroyed by use of a semiconductor diode laser.[6]


  1. Grahn B, Wolfer J (1997). "Diagnostic ophthalmology. Distichiasis and uveal cysts". Can Vet J 38 (6): 391–2. PMID 9187812. 
  2. Ketring, Kerry I. (2006). "The top ten ophthalmic mistakes" (PDF). Proceedings of the North American Veterinary Conference. http://www.ivis.org/proceedings/navc/2006/SAE/308.pdf?LA=1. Retrieved 2007-03-23. 
  3. "Anterior Uvea". The Merck Veterinary Manual. 2006. http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/30110.htm. Retrieved 2007-03-23. 
  4. Sapienza J, Simó F, Prades-Sapienza A (2000). "Golden Retriever uveitis: 75 cases (1994-1999)". Vet Ophthalmol 3 (4): 241–246. doi:10.1046/j.1463-5224.2000.00151.x. PMID 11397310. 
  5. Gelatt, Kirk N. (ed.) (1999). Veterinary Ophthalmology (3rd ed.). Lippincott, Williams & Wilkins. ISBN 0-683-30076-8. 
  6. Gemensky-Metzler A, Wilkie D, Cook C (2004). "The use of semiconductor diode laser for deflation and coagulation of anterior uveal cysts in dogs, cats and horses: a report of 20 cases". Vet Ophthalmol 7 (5): 360–8. doi:10.1111/j.1463-5224.2004.04004.x. PMID 15310297. 


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